Skip Navigation

This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrowRequest Permissions
Right arrow Disclaimer
Google Scholar
Right arrow Articles by Buckingham, J. C
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Buckingham, J. C
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

British Medical Bulletin 41:203-211 (1985)
© 1985 The British Council

research-article

HYPOTHALAMO-PITUITARY RESPONSES TO TRAUMA

Julia C Buckingham

Academic Department of Pharmacology Royal Free Hospital School of Medicine London

Abstract

Trauma influences the secretion of a number of pituitary hormones. In particular it initiates the release of corticotrophin (ACTH) which enhances the production of adrenocortical hormones essential for the organism to withstand the stressful situation. The secretion of ACTH is dependent on a neurohumoral substance, corticotrophin releasing factor (CRF), produced by the hypothalamus. The exact nature of the releasing factor is unknown but it appears to comprise several components, including a 41-residue peptide (CRF-41) and vasopressin, which act together synergistically, Its secretion is controlled primarily by excitatory and inhibitory pathways originating in other areas of the central nervous system and, to a lesser extent, by the glucocorticoids.


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 JPEN J Parenter Enteral NutrHome page
R. Minet-Quinard, C. Moinard, S. Walrand, F. Villie, B. Normand, M.-P. Vasson, J. Chopineau, and L. Cynober
Induction of a Catabolic State in Rats by Dexamethasone: Dose or Time Dependency?
JPEN J Parenter Enteral Nutr, January 1, 2000; 24(1): 30 - 36.
[Abstract] [PDF]

Home page
 The Journal of the Royal Society for the Promotion of HealthHome page
Nutrition in the Older Hospital Patient
Perspectives in Public Health, April 1, 1990; 110(2): 44 - 44.


Home page
 J Intensive Care MedHome page
A. I. Knowlton
Adrenal Insufficiency in the Intensive Care Setting
J Intensive Care Med, January 1, 1989; 4(1): 35 - 45.
[Abstract] [PDF]


Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.