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British Medical Bulletin 42:111-114 (1986)
© 1986 The British Council

research-article

THE TRANSMISSIBILITY OF DEMENTIA

J A N Corsellis

Department of Neuropathology, Runwell Hospital Wickford, Essex

Abstract

Some 20 years, ideas on the nature and the origin of cerebral degenerative disease in man were transformed by the discovery that one form, subacute spongiform encephelopathy or Creutzfeldt-Jakob disease, could be transmitted from man to animals and in exceptional circumstances, from man to man. Dementia is a main clinical feature of this condition, and the question immediately arose as to whether other dementing illnesses, and particularly those in which widespread cerebral degeneration occurs, might also prove to be transmissible. This paper attempts to outline the way in which work in this field has developed over the years and the tentative conclusions that may be drawn from it. Particular attention has been paid to the suggestion that Alzheimer's disease is a transmissible disorder but, to the writer, no convincing evidence has been found so far to support this view.


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