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British Medical Bulletin 46:156-168 (1990)
© 1990 The British Council

research-article

Factors modifying the use of anaesthetic drugs in the elderly

R M Ward and P Hutton

East Birmingham Hospital Birmingham, UK
Department of Anaesthesia, University of Birmingham Birmingham, UK

Abstract

The elderly are forming an ever greater proportion of our hospital population. The process of ageing produces a gradual erosion of all the body's margins of safety coupled with a decreasing ability to adapt. This has significant effects on the physiological responses to the surgical and pharmacological trespass encountered during anaesthesia. In addition elderly people often suffer from multiple pathology and polypharmarcy, both of which play important roles in the selection of the optimal anaesthetic regimen


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