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British Medical Bulletin 46:548-558 (1990)
© 1990 The British Council

research-article

Viral hepatitis comparative epidemiology

R Wright

Department of Medicine, Southampton General Hospital Southampton, UK

Abstract

The epidemiology of HAV, HBV, HCV, HDV, and HEV is compared. Spread of HAV and HEV is by the faecal/oral route whereas HBV, HCV and HDV are spread by blood or blood products. HEV is morelikely to produce large epidemics than HAV but sporadic cases also occur. HBV, HCV and HDV alloccur after blood transfusion, in haemophiliacs and intravenous drug abusers but they differ intheir geogrphical distribution and in the frequency of perinatal transmission which is only common with HBV. Superinfection and interaction between these viruses is discussed.


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