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British Medical Bulletin 47:493-503 (1991)
© 1991 The British Council

research-article

Prospects for the chemoprevention of breast cancer

M Baum, Y Ziv and A Colletta

Department of Surgery, The Royal Marsden Hospital London, UK
Department of Surgery, A Beilinson Medical Centre Petah Tikva, Israel
Department of Clinical Biochemistry, Cambridge Unit, Addenbrooke's Hospital Cambridge, UK

Abstract

Breast cancer is by far the most common type of cancer in women accounting for 20% of all new cases. It is estimated that 1 in 12 women will develop breast cancer at some time in their life. Each year in the UK, 24 500 women are newly diagnosed with breast cancer and 15 000 women die from it. The incidence rates rise from less than 10 per 1 00 000 women aged under 30 year to 300 per 1 00 000 in women aged over 85 years. The seriousness of the problem is emphasized by the fact that for women aged 35–54 years, breast cancer is the commonest single cause of all death.

Both the incidence and the mortality have slightly increased in recent years, although mainly in the older age groups. There has been a slight decrease in the mortality rates for women aged 15–44 years over the last 35 years, but in all the older age groups there have been increases.


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