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British Medical Bulletin 50:472-493 (1994)
© 1994 The British Council

research-article

Drug treatment: present and future

D Lyons1, J C Petrie1 and J L Reid2

1Department of Clinical Pharmacology and Therapeutics, University of Aberdeen UK
2Department of Medicine * Therapeutics, Gardiner Institute, Western Infirmary Glasgow, UK

Abstract

The objectives of drug therapy – present and future – for the treatment of raised blood pressure are to prevent the morbid and fatal events which arise in individual patients as a consequence of poorly controlled levels of elevated systolic and/or diastolic blood pressure. The target levels of blood pressure require to be achieved without adverse effects at an affordable cost, over a prolonged period of years. The factors affecting the choice of drugs in such patients include the ‘profiling’ of the blood pressure to assess the severity of the hypertension, associated diseases and risk factors, concurrent therapy, inter-individual variations in response between patients and cost-effectiveness.


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