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British Medical Bulletin 51:717-746 (1995)
© 1995 The British Council

research-article

Prospectives for cutaneous malignant melanoma Considerations of the precursor state and heritability

W H Clark, A M Goldstein and M A Tucker

Department of Pathology, Harvard Medical School, The Benth Israel Hospital Boston, MA, USAPathology Services Inc. Cambridge, MA, USAThe Pigmented Leison Group, University of Pennsylvania, School of Medicine Philadelphia, PA, USA
Genetic Epidemiology Branch, National Cancer Institute USA Bethesda, MD, USA

Abstract

Each of the discoveries through the years has begotten a series of Gordian knots. We must patiently inspects our new collection of mysteries and focus on those where our efforts may well change the course of the disease to the benefit of affected patients. The proper management of the precursor state, the begining of the disease, and the patient exploration of the complexities of heritability would seem to be appropriate beginings.


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