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British Medical Bulletin 66:305-316 (2003)
© 2003 The British Council

Ethical issues in human prion diseases

S J Tabrizi*,{dagger}, C L Elliott* and C Weissmann*

* Department of Neurodegenerative Disease/MRC Prion Unit, Institute of Neurology, London, UK
{dagger} National Hospital for Neurology and Neurosurgery, London, UK

Prion diseases or transmissible spongiform encephalopathies are a group of closely related transmissible neurodegenerative conditions of humans and animals, all of which are incurable. In recent years, they have captured public attention with the emergence of the bovine spongiform encephalopathy (BSE) epidemic in Europe, and more recently with the appearance of variant CJD (vCJD) in humans, a novel form of Creutzfeldt-Jakob disease (CJD) that is linked to dietary exposure to BSE1–3. In this chapter, we outline ethical questions posed by research, diagnostic procedures and therapy in the field of prion diseases.


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