British Medical Bulletin 68:129-142 (2003)
© The British Council 2003; all rights reserved
Environmental effects and skin disease


* Department of Dermatology, Queens Medical Centre, University Hospital, Nottingham and
Department of Dermatology, Ninewells Hospital, Dundee, UK
Correspondence to: Dr JSC English, Department of Dermatology, Queens Medical Centre, University Hospital, Nottingham NG7 2UH, UK. E-mail:john.english{at}mail.qmcuh-tr.trent.nhs.uk
The skin is the largest organ in the body and one of its main functions is to protect the body from noxious substances, whether they are ultraviolet radiation, toxic chemicals or prolonged/repeated exposure to water. It is the level of exposure that determines if damage to the organism will result. The harm that can occur to the skin with sufficient exposure will be considered. Contact dermatitis, halogen acne, chemical depigmentation, connective tissue diseases and skin cancer are the conditions that will be covered in this chapter, as environmental exposure is important in their aetiologies. Systemic absorption will not be dealt with. Most environmental exposure to harmful substances will occur at work, but exposure may occur at home or during normal day-to-day activities.