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British Medical Bulletin 2005 73-74(1):123-137; doi:10.1093/bmb/ldh054
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Published online 22 December 2005

© The Author 2005. Published by Oxford University Press on behalf of The British Council. All rights reserved. For permissions, please e-mail: journals.permissions@oupjournals.org

Lessons from nosocomial viral haemorrhagic fever outbreaks

Susan P. Fisher-Hoch

Department of Epidemiology, University of Texas Houston Health Science Center, School of Public Health, Brownsville Campus, Brownsville, TX, USA

Correspondence to: Prof Susan P. Fisher-Hoch, MD, UTHSC-SPH Brownsville, 80 Fort Brown, Brownsville, TX 78520, USA. E-mail: susan.p.fisher-hoch{at}utb.edu

The outbreak of Marburg haemorrhagic fever in Angola in 2004–2005 shows once again the devastating and rapid spread of viral haemorrhagic fevers in medical settings where hygiene practices are poorly applied or ignored. The legacy of years of war and poverty in Angola has resulted in very poor medical education and services. The initial high rate of infection among infants in Angola may have been related to poor hospital practices, possibly administration of vaccines. Though the outbreak in Angola was in a part of Africa not previously known to have filovirus infection, prior ecological modelling had predicted this location and many others. Prevention of future outbreaks will not be easy. The urgent need is dissemination of knowledge and the training, discipline and resources for good clinical practice. Educating the public to demand higher standards could be a powerful tool. Good practices are difficult to establish and maintain on the scale needed.


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