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British Medical Bulletin Advance Access originally published online on July 1, 2008
British Medical Bulletin 2008 88(1):147-156; doi:10.1093/bmb/ldn024
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© The Authors 2008. Published by Oxford University Press. All rights reserved. For permissions, please e-mail: journals.permissions@oxfordjournals.org

Intermittent pneumatic compression in fracture and soft-tissue injuries healing

Anil Khanna{dagger}, Nikolaos Gougoulias and Nicola Maffulli*

Department of Trauma and Orthopaedic Surgery, Keele University School of Medicine, Thornburrow Drive, Hartshill, Stoke-on-Trent, ST4 7QB Staffs, UK

* Correspondence to: Nicola Maffulli, Department of Trauma and Orthopaedic Surgery, Keele University School of Medicine, Thornburrow Drive, Hartshill, Stoke-on-Trent, ST4 7QB Staffs, UK, E-mail: osa14{at}keele.ac.uk

Introduction: Current methods of fracture care use various adjuncts to try and decrease time to fracture union, improve fracture union rates and enhance functional recovery. Intermittent pneumatic compression (IPC), one such modality, is used in the management of both fractures and soft-tissue injuries.

Methods and results: A search of PubMed, Medline, CINAHL, DH data and Embase databases was performed using the following keywords ‘intermittent pneumatic compression’, ‘fracture healing’ and ‘soft tissue healing’. Sixteen studies on the use of IPC in fracture and soft-tissue healing were identified. These studies demonstrated that IPC facilitates both fracture and soft-tissue healing with rapid functional recovery.

Conclusions: IPC appears to be an effective modality to enhance fracture and soft-tissue healing. However, the number of subjects in human studies is small, and adequately powered randomized controlled trials in humans are required to produce stronger clinically relevant evidence.

Keywords: intermittent pneumatic compression • fracture healing • soft tissue healing

{dagger} Anil Khanna is a DePuy International Implant Research Fellow

Accepted for publication June 9, 2008.


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