British Medical Bulletin Advance Access published online on September 23, 2008
British Medical Bulletin, doi:10.1093/bmb/ldn035
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Social cognition in schizophrenia: a review of face processing
Division of Psychiatry, University of Edinburgh, UK
* Correspondence to: Dr J. Hall Division of Psychiatry, University of Edinburgh, Kennedy Tower, Royal Edinburgh Hospital, Edinburgh EH10 5HF, UK. E-mail: jhall5{at}staffmail.ed.ac.uk
Background: People with schizophrenia have difficulties in interpreting social information. Much social information is gathered from faces, and face processing represents a well-characterized model to study the basis of social deficits in schizophrenia.
Sources of data: A narrative review of selected literature.
Areas of agreement: Individuals with schizophrenia have impairments in recognizing basic emotions and making social judgements from facial stimuli.
Areas of controversy: The neural basis of these abnormalities is still being determined. However, initial evidence implicates dysfunction of frontal and temporal lobe brain regions. Hyper-activation of the amygdala, a brain region involved in fear, to facial stimuli may be an important underlying neural abnormality.
Growing points: The present article highlights the difficulties that people with schizophrenia have in interpreting social cues from faces.
Areas timely for developing research: Research is required to understand more about both the basis of social deficits in schizophrenia and their potential remediation.
Keywords: Emotion identity functional outcome fMRI social judgements amygdala
Accepted for publication September 2, 2008.