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British Medical Bulletin Advance Access published online on November 17, 2009
British Medical Bulletin, doi:10.1093/bmb/ldp043
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© The Author 2009. Published by Oxford University Press. All rights reserved. For permissions, please e-mail: journals.permissions@oxfordjournals.org

X-ray computed tomography of the heart

Nevin T. Wijesekera, Mark K. Duncan and Simon P. G. Padley*

Department of Radiology, Royal Brompton Hospital, Sydney Street, London SW3 6NP, UK

* Correspondence to: Dr S. P. G. Padley, Department of Radiology, Royal Brompton Hospital, Sydney Street, London SW3 6NP, UK. E-mail: s.padley{at}rbht.nhs.uk

Introduction: Cardiac imaging is an emerging application of multidetector computed tomography (MDCT). This review summarizes the current capabilities, possible applications, limitations and developments of cardiac CT.

Sources of data: Relevant publications in peer reviewed literature and national and international guidelines are used to discuss important issues in cardiac CT imaging.

Areas of agreement and controversy: There is broad consensus that coronary CT angiography is indicated in patients with an intermediate pre-test probability of coronary artery disease (CAD) when other non-invasive tests have been equivocal. In this context, CT can reliably exclude significant CAD. Cardiac CT also has an established role in the evaluation of bypass grafts and suspected coronary anomalies. Radiation exposure from CT procedures remains a concern, although techniques are now available to reduce the X-ray dosage without significantly compromising the image quality. However, with the current level of knowledge, the cardiac CT examinations are not justified to screen for CAD in asymptomatic individuals. Neither is it considered appropriate in patients with a high pre-test probability of CAD, for whom invasive catheter coronary angiography is usually of more benefit.

Growing points and areas timely for developing research: The ability to reconstruct the volumetric cardiac CT data set opens up avenues for advanced physiological analyses of the heart. For example, if CT myocardial perfusion assessment becomes a reality, there is potential to revolutionize the practice of MDCT imaging. Research is also ongoing to investigate whether cardiac CT has a role in the appropriate triage of patients with chest pain in the emergency department.

Keywords: multidetector computed tomography • coronary angiography • cardiac

Accepted for publication October 20, 2009.


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