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British Medical Bulletin Advance Access originally published online on December 14, 2006
British Medical Bulletin 2006 79-80(1):171-186; doi:10.1093/bmb/ldl013
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© The Author 2006. Published by Oxford University Press. All rights reserved. For permissions, please e-mail: journals.permissions@oxfordjournals.org

Positron emission tomography in oncology

Jonathan D. Berry{dagger} and Gary J. R. Cook{ddagger},*

{dagger} Department of Radiology
{ddagger} Department of Nuclear Medicine and PET, Royal Marsden Hospital, Downs Road, Sutton, Surrey SM2 5PT, UK

* Correspondence to: Dr G. J. R. Cook, Department of Nuclear Medicine and PET, Royal Marsden Hospital, Downs Road, Sutton, Surrey SM2 5PT, UK. E-mail: gcook{at}icr.ac.uk

Increasing access to positron emission tomography-computed tomography (PET-CT) has resulted in a shift towards functional imaging, being the primary tool in the assessment of viable tumour in oncology patients. In this review, we discuss the basic principles of this evolving technology and the radio-isotopes it employs. The main clinical applications of PET-CT are reviewed and some of the limitations of the technique are highlighted. Finally, we offer insight into possible future developments and how these modify current practice.

Accepted for publication November 1, 2006.


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